Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

SSRI or 5HTP with movement disorder? » desolationrower

Posted by sowhysosad on April 8, 2009, at 17:01:08

In reply to Re: Fluoxetine/sertraline and dopamine, posted by desolationrower on April 8, 2009, at 8:24:48

> haven't really looked into mnovement disorders but why would 5htp not exacerbate it if ssris would?
>
> -d/r

I'm guessing that 5HTP wouldn't interfere with other systems in the brain like SSRI's do, like the aforementioned D2 supersensitivity issue. 5HT2A/C agonism from SSRI's could also be a factor, plus there's a theory that they may also cause movement disorders by acting on sigma 2 receptors in the red nucleus.

I'm also guessing it would also be easier to fine-tune serotonin levels with 5HTP, rather than arbitrarily flooding the synaptic gap as SSRI's often do. Presumably this would make it easier to strike a balance with dopamine, as its release wouldn't be mediated by the abnormally high serotonin levels.


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:sowhysosad thread:887980
URL: http://www.dr-bob.org/babble/20090408/msgs/889517.html