Psycho-Babble Medication | about biological treatments | Framed
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Re: Seroquel's DA/SA lowering + Nardil = Depression?

Posted by bleauberry on March 1, 2009, at 16:32:54

In reply to Seroquel's DA/SA lowering + Nardil = Depression?, posted by myco on February 28, 2009, at 21:32:50

I would explore a different sleep med. It makes zero sense to me to take something that makes me feel worse...on purpose...and expensive...and then go out and have to toy with something to make me feel better while continuing taking the thing I know is making me feel worse. I don't get that.
Though I do admit, been there done that.

There is other stuff. Lunesta, klonopin, restoril, 7.5mg remeron, trazodone (I hate this one, but hey, some people like it), and how about nortriptyline or maybe cautiously amitriptyline.

If you want an antipsychotic induced sleep, Zyprexa is in my opinion a better choice overall for just about any psychiatric condition. It doesn't have the knockout punch of Seroquel, but it is definitely a sleep inducer and in my opinion is a much better psych med all around.

And the stuff about tyrosine and tryptophan. Well, it aint quite so easy. All that stuff assumes that your genes and your enzymes are going to convert those things into the things you want and through the correct pathways. That's an iffy assumption in anyone with ongoing psychiatric symptoms.

I wouldn't mix either of those with an MAOI anyway.

Seroquel isn't lowering DA or SA, it is actually increasing them as well as NE. Brain concentrations of all three increase on Seroquel or Zyprexa or Risperdal. But at the same time the receptors are being partially blocked from feeling the extra boost.

Personally I would either...increase the dose of Seroquel to see if it feels different in terms of mood, maybe takes on a different character, or ditch it completely and resume the hunt. There is no perfect med that lasts forever, so sometimes you gotta learn to live with the best you got at the time.


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