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Re: MAOI - Is insomnia a good sign of future response? SLS

Posted by myco on February 10, 2009, at 13:32:09

In reply to MAOI - Is insomnia a good sign of future response?, posted by SLS on February 10, 2009, at 11:22:58

> When I was most responsive to MAOIs early in my treatment history, this was a sign that I would eventually respond to the drug I was taking, whether it was Parnate, Nardil, or clorgyline.
> * Clorgyline is no longer available.
> Would anyone like to share their experiences with MAOI drugs and insomnia and whether they eventually responded to the drug?
> Unfortunately, quite a few people abort MAOI trials because of insomnia instead of being aggressive in remediating this side effect. I took two different benzodiazepines at the same time to treat the insomnia when it appeared.
> Thanks.
> - Scott


I definately agree that insomnia corresponds with nardil response for me. I would sit at a dose of nardil for weeks even after I know/believed the dose had died (although this wasnt always the case - nardil has this strange kick back up again effect for me) and my sleep would improve from 2 to 4 hours a night up to 7 or 8...of course anxiety and depression would be creeping back up nicely. But during those first two good weeks of response at each dose level raised to, the insomnia was exquisite. Now 75mg is stable for me and going strong and insomnia is my shadow. Someone here, can't remember where, mentioned a pattern in their sleep with parnate (i think it was?) with 0 sleep one night then 4-5h the next...cycling back and forth. I agree with this also. Doesnt matter my sleep med now, 2-4h at best nights followed by almost none the next or two days a cycle for this my effective dose.
Im not sure how much this helps but im not that knowledgeable with biochem to help make sense of this to your level. I'm just very intune with my own mannerisms and body.





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