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Re: Parnate - Evidence for using high dosages. » JadeKelly

Posted by Vincent_QC on December 28, 2008, at 11:36:58

In reply to Re: Parnate - Evidence for using high dosages. » Vincent_QC, posted by JadeKelly on December 28, 2008, at 10:33:07

> Hey Vincent!
>
> I haven't talked to you for a while. Hope you had a good holiday! It stinks the hoops we have to jump thru to get the medications we NEED. Normally I would not do things behind my Docs back but what chance would you have at 30 mg? Just make sure you don't get them filled at the same pharmacy, haha. Also you should stay at each dose for a little while. I was at 30mg for 6 weeks, but that was cause I had a problem with my BP. It took me 10 weeks to get to remission (60mg day) and my only real side effect was disruption in sleep, either insomnia, or couldn't get out of bed. Oh, be careful with low BP, I think you had this problem already, I came really close to fainting a few times. You will probably lose weight. So if you don't work, then you should be able to do this. You have family at home, right? Don't Quit! Even if you feel like it. I have never responded to any other A/D.
>
> Good Luck!
>
> ~Jade

Hi Jade,
Thanks to take some of your times to answer to me, that's really appreciate ;-)

I also don't like the idea to play in the back of my psychiatrist, but with time we learn to find some tricks to help us to have what we want. The fact that I prefer my family doctor is because he is very open minded, I meet him every month or so, sometimes I bring papers about drugs I found on the internet or in books, and I ask him what he think about this or thas idea, if it will help me, things like that...We try several drugs that come directly from my research (Lyrica, Gabapentin, Topamax, Nardil...), it was not his idea...it was all mines...So it's why I feel more free with him to try what I want and to explore all the possibilities I can have with one medecine. He also don't say bad comments about drugs like benzodiazepines and the fact that if I continue to take them I will never recover from my social phobia...that what my psychiatrist told me the last time I see him...I know that i'm addicted to them but he don't have to remind me that I will have to quit them as soon as I will be stable on the Parnate...he put too much pressure and stress on me by telling me this. I try severals times to stop them but that's not the time for now... Anyway the Parnate seem to be effective on that field, I take 5mg less of valium by day (15mg/day, before 20mg/day) since i'm on 30mg of Parnate.

Yeah, sadly, with MAOI's, blood pressure is a bad issue, you know what I mean...my Nardil experience back in 2007 was desastrous, my doctor said for 3 months don't give up, and I give up at 90mg/day, I was so tired....but at the time, he was not aware about the Florinef drug and the fact that this drug can control the hypotension and orthostatic problems...

My blood pressure return to the normal now. I had a lot of orthostatic hypotension the 24 december, it's why I wrote a message here, to find some help, and I find the answer I wanted...I continue to experience a little bit of orthostatic hypotension sometimes...but I get use to it now and that's less bad than on the Nardil...it'S on and off...

Yeah I experience some low blood pressure sometimes, but just when I climb the stairs...and that's strange cause it's not considering like orthostatic hypotension, orthostatic hypotension is suppose to happen when you are sit down and you decide to get up of a chair or the bed or things like that...Anwyay, I monitor my blood pressure several times by day with my own machine, and I know what I do...

I also experience insomnia at night, like you, and stranglely, I can sleep at day time...I sleep more well at day time...but I was like this before the Parnate, so I don'T know if it come from it or not. Fatigue is also a lot present, but I was like this before...I don't think Parnate deteriorate my state on this 2 sides...it'S just the same...no improve...My motivation level is low also, but I was already like this before...

For my blood pressure, I decide to begin again to take the "Florinef" pills, to help me with the orthostatic hypotension problem and to prevent it, and for the high blood pressure, I always have with me the "Antidote"...Neftidine or a name like this, I never remember it...but it's a yellow pill, with liquid inside in a very hard coating, I think it's a slow release...10mg...but my family doctor said it's perfect and if my blood pressure go up to 180/90...I can take one without any problem and without having to go to the hospital, he said to just take my blood pressure more often if I do a hypertension crisis and take one Nefidine pill...

You know, I don't want to stay at 30mg for 6 weeks like you...I know myself, and I know I need more high dose to feel some relief, I don't want to jump to 60mg in 2 weeks, I just want to increase it at least at 40mg and stay at this point for maybe 2 weeks, to see what happen, if I don't do more orthostatic hypotension and low blood pressure (anyway Florinef will take care if it by recycling the salt inside my body and make my blood pressure more high like this), I will continue a little bit at this state and see what happen, if I don'T improve more, I will jump to the 50mg...and do the same...I know MAOI's take some times to be effective, more than newer drugs...but I don't think 40mg, 50 or 60mg it's an abuse of this substance...

My goal is not to become a zombie or to have more side effects than good effects...I just want to feel normal again and be able to go outside my house without freaking out about the others people I will have to meet or see...I want a "normal" life again and be able to continue the university, have a job and be someone who is fonctionnal in the life...

Hummm, for now, I return live with my mom...Thanks god, she's was very nice and understing with me...Before, I was leaving in another city for studying at the university...it was a big city and at the end I was unable to take the subway or go outside my appartement, and I had no friend at all... so when I begin to feel worst and worst, after some years of relief with social phobia and anxiety, I decide to return to the city where I came from and be near my familly, to have more support...I stop school, ask for a suspension of my folder, and for now I have no plan for the future, except to recover from this hard period I have...

And yeah, i'm also like you...I never answer to an AD before...I just had a small relief at the begining of my Rivotril treatment, but I had to augment my dosage regulary...to the point of no return...From 19 to 24 yo, I had some small improve on Paxil, it was the newer drug at the time...but I think it was not working at all, the therapy I do at the time help me more...with time I can say that Paxil was innefective...I just gain a lot of weight on it... All the others newer AD never help also, always feeling worst after trying them, especially Effexor and Cipralex (LExapro)...Zoloft do nothing at all at the highest dose and Luvox also...PRozac make me more anxious, Remeron make me gain weight and sleep more but that's it, Celexa do nothing at all, even at 60mg/day...Elavil and Impramine do nothing also...Wellbutrin make me feel anxious a lot...Anticonvulsives drugs do nothing (Gabapentin- Neurotin, Lyrica, Topamax...I had electric shock sensation on them), Antipsychotics drugs do nothing, it was ridiculous and I had terrible hands shaking on them (Risperdal, Zyprexa, Seroquel...), and the list goes on..I try others things as well but don't remember all of them...Stimulants was helping with the fatigue but not with the anxiety...(Ritalin) ...so I think I never responded to a drug at all...Nardil improve me a little bit but the orthostatic hypotension was too hard to support...it help me to reduce my Rivotril intake at the time...and I was able to switch from the Rivotril to Valium (less addictive benzo)...but for the social anxiety I don't improve, my general anxiety improve a little bit on it... The only 2 drugs I don't try for now are Cymlabta and MAnerix (you don'T have it in the USA I think....it'S a reversible MAOI's of type A, not very effective for social phobia aparrently, somes studies show it was effective, others not...it's why the FDA never approve it in the USA) so i'm not interrested at all...Cymbalta is nothing more than another effexor type drug...so no thanks...

Well, that's was another chapter of my books!!! Sorry it was long again...

Have a nice day and don'T give up, i'm very happy for you that the Parnate finally work !!! That's a great news!!!

Bye!

Vince ;-)


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poster:Vincent_QC thread:871054
URL: http://www.dr-bob.org/babble/20081223/msgs/871159.html