Posted by bleauberry on December 20, 2008, at 10:40:53
In reply to Minimum dose of Zoloft with augmentation drugs?, posted by dcruik518 on December 20, 2008, at 9:00:25
300mg Traz is a huge dose. Most people take 25mg to 50mg, sometimes 100mg, for sleep. I suspect many people would feel like they had been hit with an elephant dart at 300mg Traz. It does have a short halflife, but still, I've taken 25mg at bedtime before and still felt the lethargy from it up until about late afternoon the next day.
Even with its short halflife, you still have about 150mg of it in you when you get up in the morning, which is a higher dose than most people take at bedtime. And by lunchtime you still have about 75mg left, again, a normal bedtime dose. I don't know, maybe you have developed a tolerance to it or something, but me, that would knock me out for days.
By looking at 50mg zoloft versus 100mg, I just kind of wonder if you aren't looking in the wrong place. If I were to try reducing anything, it would be traz. You didn't mention the dose of abilify, but that is certainly just as much a suspect as anything else.
It does get difficult to know what is doing what when there are several meds. Sometimes it isn't any one med in particular, but rather a synergistic phenomenon that only exists with the mixture but not with any individual med. You kind of have to follow your gut instinct on this one, because there is no way to tell. But from an outsider's point of view, that 300mg Trazodone took center stage, with the abilify right on its heals.
poster:bleauberry
thread:869814
URL: http://www.dr-bob.org/babble/20081214/msgs/869823.html