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Re: Tell Me All About Parnate » desolationrower

Posted by uncouth on November 22, 2008, at 19:37:48

In reply to Re: Tell Me All About Parnate » uncouth, posted by desolationrower on November 22, 2008, at 18:54:58

honestly, it's hard to tell. i'm in general not so good about being able to tell specifically how psychotropic drugs effect me except over the long term (e.g., it took me 2 years and a severe depression to realize just how much of my compulsive internet use, eating, and lack of libido was due to SSRIs)

but i find that I don't even really notice the additional deprenyl. even if i take 5mg one day instead of 2.5 (and i take the oral pill form, not the sublingual solution form) it's hard to tell that i'm taking anything.

if your shooting for the neurotrophic effects and the beneficial antioxidant stuff, i think 10mg a week should be a good target, or 2.5mg every other day or so.

if your on an MAOI already, 10mg a week is actually enough to provide some meaninful MAO-B inhibition, so i'm not sure what that would mean for the other MAOI (like i'm on parnate 80mg). It may mean the other MAOI has more room to attack MAO-A, or it may just mean that MAO-B is essentially being hit by two different drugs and thus 100% inhibited, which i think for people depressed, especially those who when euthymic still have lots of anhedonia, attention problems, and other dopamine connected things, a very good thing.

 

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URL: http://www.dr-bob.org/babble/20081114/msgs/864761.html