Posted by jnew12 on November 4, 2008, at 10:42:35
For me, Xanax and Klonopin do not work quite the same as they do on Nardil. Does it have something to do with how Nardil already inhibits that GABA enzyme? I actually believe I need less klonopin, and xanax know that I am on a MAOI, because it messes with I thin it may mess with it's effects, is that true for other people? For me Nardil takes away the anti anxiety properties of benzo's and just makes me sedated.
Lyrica on the other hand I thin is the augmentator. It is very easy to get, I had a doc throw it at me, it is FAST ACTING, and some say it make you feel like your on GHB on high doses. Low doses don't do nothing but sedate you, and make you feel out of it. But when you get into the 400-600mg range it actually SPEEDS you up, give you EUPHORIA, and actually for me totally change the WAY I FEEL. But it is not without side effects, I feel dizyness, If you take it you will probably feel like your stoned, and some may people may comment that your eyes look glazed- like they do me, also for some reason you eat like a pig (Does anyone else get this effect).. The eating part is good for me, because it takes away my nausea (I have a vomiting disorder called- Cyclical Vomiting Syndrome. But, it is a pretty benign drug and really easy to get. All you have to do is say that you have some nerve pain, or fibormyalgia, that is easy for a doc to believe because people with fibro are alway depressed. And if your depressed you might feel some pain, I know I do. I think that is why they advertise cymbalta for pain. But, actually it has been approved in EUROPE for General Anxiety Disorder I think, and also been recommended for Social Anxiety, I read many people approve of it in books, and med sites like pub med, and using google scholar.
If your psychatrist has heard of it he might prescribe it for those reasons, psychs used to give out it's little brother neurotin (which is no way as good I think). I have not tried neurotin though..does anyone know if it works as good as lyrica for anxiety? I know it was used for mood stablization.
Lyrica though, is pretty easy to get from a regular doctor, or registered nurse. Some love this drug, as my doctor does.
Beware, there is mild WD when coming off it, less that benzo WD though, you will feel a little sick, and want to vomit. Low doses are easy as cake, but if your on a dose high is me (400mg -600mg) then you will have to taper .
Your doctor will start you off at a low dose maybe, 25mg twice a day, or 50mg, twice a day. If you like it, demand more say it works well. I started off at at least 100mg, and worked my way up too 200mg, for a complete change in behavior, attitude, altered consious, changed thinking try 400mg. The max is 600mg, that is a little hard to get that is why I only get 400mg from my doc. But, when I feel like changing my mood and ablerterating anxiety I take 600mg one day, and 200mg the next so I don't run out early.
It seriously alter how you feel in every way, your personality, your thoughts, your speech, you walk.By the way it is also totted as NON-ADDICTING, they will even give it to substance abuser for some reason, although it is scheduled but I think it's a lower lever than even benzos?
My doctor will not prescribe Ritalin, or Adderal XR, because they are highly contradicted and some say here it is a recipe for disaster. You don't want to go to the hospital. I went behind my PDOC back and got some Adderal, I tried it with Nardil a couple times (maybe like 4) I did not get any hypertension even at doses 40mg of adderal xr, but now looking back it was not a good idea, and I and you don't want to risk it getting hypertension, and I didn't want my doctor find out I was taking without his knowledge so I stopped. Does anyone else do, or ever took a stimulant without the doc that give you MAOI's knowing? If you really want to try adderal xr make sure you doctor knows don't do what I did! Do you think he will find out, I see him today, and I don't want him to take it away yet.
If you doctor is well versed in MAOIS, and has read many studies, you might get a low dose of dexedrine which is like adderal, but has one amphetamine salt, instead of four, I think this is why it is less dangerous. That is true yet? I still think it's dangerous.
Even Provigil is contradicted and a doctor who is not versed in MAOI probablly will not perscibe that either. I really want to try PROVIGIL.. do you think it is a stupid idea to order progvigil online, because it is less risky? I probably wont. But I really want to try..because Nardil give me HEAVY sedation,and hypotension . I think Provigil is less dangerous than the highly scheduled amphetamines, and dopamine antagonist. Do you think it will help with Sedation, Concentration, and hypotension, if so I really want provigil. But, still probably would not take it with out caution it still effect some of the same receptors as Anti Depressant and Stims, which are not allowed I think, right?
I would not personally augment it with lamictal, lithium, or any antipsychotic, unless I was bipolar or heard voices, This will probably make me sedated as heck, even though they are not contradicted I don't think it's worth a try. How many others here take lamicatal, lithium or anti psychotics with a MAOI?
I think Benzo's do have there place but probably are better tolerated with parnate then nardil, because again nardil affects the enzyme that inhibits GABA. So, it may react differently there was someone who took a benzo with Nardil, and had a panic attack, which was very strange, but belivable, because of how I think it changes the effect of drugs like klonopin, xanax, and valium.
If you really have to take a benzo like I do sometimes take one, out of the three benzos, I would take Xanax because it is fast acting, and gets out of your system quick so you don't build a tolerance.
Xanax is very effective for night time insomnia too.
Another thing people augment nardil with is T3, the pill is called cytomel and it speeds up your thyroid, and metabolism I think. One doctor put me on it because he said it augments antidepressants and make them work faster, I actually got more energy and enjoyed it, but then two other psychatrist said they never heard of it, and one took me off it because he said that was a stupid idea.
But, here I read people augment with T3 all the time. I wonder what the true reason is for?
It would not hurt to try, I really don't know how it reacts on other people, and I don't know if it will give you energy like it did me because it is not a stim.
Another drug that is highly effective for treatment resistant depression is buprenorphine.
I get it for generalized pain, and was also given it to get off a stronger opiate i was taking, methadone and morphine.
It is non addicting, the effects are not that noticable but it has been proven to work on depression. And, for me it's the second best augmentor for nardil, behind lyrica.
In the US, physchatirst and doctors have to have a special license to prescribe it, so if you live in another country I don't know if you can get it. If you live in Europe you will probably get it easy because they use it for PAIN more than they do in the US, because it is not offically FDA recommended for pain in the US right now, but I think it will, or should be soon.
If you get it, it probably wont be for depression anyways, unless you had a real cool doctor, or someone who reads the studies and is willing to help. Read the studies it works BUPE works GREAT for DEPRESSION for a lot of people.
Nardil has not been working well for me as of late, unless I augment it with lyrica, and buprenorphine because I don't know if it has kicked in yet, I have been taking it for a month, I will give it one more month and if it does not work, I am switching to parnate or getting off antidepressant all together, and just use anti-anxiety agents. I have tried a bunch of anti D's (zoloft, remeron, effexor, paxil, lexpro, trazadone, anafranil, prozac, ritalin, adderal, and probally many more) I just don't antidepressant are for me, I even read in some studies MAOI's are no more effective, than the newer SSRI's and if that is true I am screwed. That means I will probably have to wrestle with depression all my life. There is also studies (KIRSH) saying that antidepressants are no more effective that placebo. Again if that is true, I will probably end up living a sub par life- either on disability, or floating around, I just hope that I dont turn to drugs, or suicide.
I think Nardil has real bad effects on my concentration, another reason I wish I was prescibed a stimulant, but oh well, stimulants don't work as well on social anxiety as they do on depression and ADHD anyways.
Oh yeah, I make sure I take a B-Complex because nardil has been proven to deplete vitamin B-6. I would also take a multi vitamin.
It is also great to take something with DHA, and EPA, like fish oil, and flax seed. I put a bunch of flax seed on my oatmeal everyday. Fish oil is better though, actually HEMP has the most balanced EPA, and DHA, for the human body. EPA, and DHA, have been studied and been proven to calm the mind, and help with disorders like depression and anxiety, good for the mind. And, does not interact at all.
Also, do not drink protein shakes, they may be healthy but some contain SOY (which is contradicted) and a lot have a ton of Amino Acids, some have even more added because amino acids are really good for you but, in most blends of amino acids there is TYROSINE which is basically the pre-curser to TRYAMINE, I may be mistaken but I think I read that somewhere. If you took a Tyrosine pill (which is stimulating) you would probably have a trip to the hospital because of it's filled with TYRAMINE, even more than aged CHEESE I think.
Ok, that about sums it up. Good luck with the Nardil! I hope it kicks in for me, or it's the blue for me..........
poster:jnew12
thread:860727
URL: http://www.dr-bob.org/babble/20081027/msgs/860727.html