Posted by bulldog2 on October 16, 2008, at 11:39:37
In reply to Could this be possible? Small dose nortriptyline, posted by hansi555 on October 16, 2008, at 11:31:21
> Hi all
> I am in the middle of the proces of switching from a combo of Lexapro 25 mg and Remeron 35 mg to a correct dose of nortriptyline.
> As agreed with the PD I lowered the Lexapro gradually from 25 to 20, 15 and now 10 mgs over some weeks time. At the same time I went from 25 to now 50 mg Nortriptyline.
> I have decided to make the switch as I have many of the melancholic features; morning worsening, no appetite, no lust etc. that the combo Lex/Rem did not help with.
> Now the strange thing is that the morning after taking the first 25 mg of Nortriptyline, I felt beter than in a long time and the second day, I felt great (as if I was not ill anymore) and so it was the next 7-8 days - at this time I was on 20 mg Lexapro and Remeron 35 mg unchanged.
> It was like this small dose of Nort just hit the missing spot for me in a way that Lexapro could not on its own.
> As I increased the Nort to 50 mg and lowered the Lex dosage to first 15 mg and later 10 mg some days ago my mood went slightly downwards.
> I am quiet puzzled here.
> Could it be that such a small dose (25 mg) of Nortriptyline can work within a few days?
> I was expecting all sorts of bad SE but nothing happened, only a bit of dry mouth (which after increasing to 50 mg is somewhat annoying now)
> I am now wondering if I should go back to the 20 mg Lexapro and 25 mg Nort again and just see what happens or just stick to the PD plan of dropping the Lex completely and increase the Nort.
> Any thoughts?
Yes I would retest at the combo that worked you may have just hit the correct ratio.