Posted by Quintal on October 6, 2008, at 2:18:31
In reply to Tianeptine and Agomelatine, posted by Trotter on October 5, 2008, at 17:20:05
I've taken tianeptine on and off for years and it has always worked when I came back to it. I had a very nasty bout of depression in June and tianeptine brought me out of it and back to normal in under a week. I've been taking it for three months now (the longest I've ever taken it) and it works just the same as it did in the beginning. I suppose the degree of remission depends on what sort of response you're looking for from a med. I just want to feel mellow and content with the world, and I find tianeptine is great for that. Someone looking for something to rev them up and give that 'ready to take on the world' type of feeling may feel they're not getting the full antidepresant response they want from tianeptine.
The biggest problem I've had is that it sometimes causes 'spaciness' and lack of focus. I presume this has something to do with its anti-NE effect. I also take Lamictal and I think that contributes to the poor focus. I have tried adding noradrenergic meds to it with some success, but they come with their own problems.
The thing I like most about tianeptine is that I still feel the full spectrum of emotions, and of course that my sexual parts are still functioning. It is a good med and I recommend it to everyone who has had no luck with SSRIs etc. It doesn't work for everyone, and sometimes people try to ruin it for people who have, but I'd recommed you give it a good long trial - provided nothing untoward crops up of course. I too am very excited about agomelatine and it is high on the list of meds I want to try next, as much out of curiosity as anything else. I hope tianeptine works well for you.