Posted by Larry Hoover on October 4, 2008, at 17:50:25
In reply to Thyroid levels and Serotonin, posted by bulldog2 on September 27, 2008, at 19:11:43
> T3 (the active thyroid hormone created from T4 in the liver by the 2D6 enzyme) desensitizes presynaptic serotonin autoreceptors
I believe that this source is wrong. T4 is a substrate for cytochrome 3A4, not 2D6. And that's a good thing, because some people have no 2D6 function whatsoever.
3A4 function/rate is influenced by many drugs, and by diet (e.g. the grapefruit effect). Makes you wonder what happens to T3 levels.