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Re: The stakes are too high. » SLS

Posted by Cecilia on August 22, 2008, at 0:25:23

In reply to Re: The stakes are too high. » Cecilia, posted by SLS on August 20, 2008, at 8:03:35

> Don't get mad at me for trying.
>
> Something I read recently demonstrated that, for certain drugs, more is better when it comes to a starting dosage to avoiding side effects. Prozac and Geodon are examples. Prozac at 20mg is probably less problematic than at 5mg. At lower dosages, it can be anxiogenic, at higher dosages it becomes anxiolytic and antidepressive. The same thing has been shown to be true of Geodon. It is less problematic at 40mg than it is at 20mg. I wonder if Abilify follows a similar pattern. I also wonder if at lower dosages, Effexor is more dopaminergic relative to serotonin and norepinephrine and more likely to produce a nausea that lingers.
>
> With Abilify, I started at 20mg. I had very little problem with agitation, restlessness, or anxiety. The doctor who managed me was pretty smart.
>
> Anyway, I am still on your side, even if my current positive outlook becomes annoying.
>
> Any chance of mixing Wellbutrin with Lamictal?
>
>
> - Scott
>
>
>
I'm not mad at you, just frustrated and hopeless. Maybe it's theoretically possible that for some meds higher doses have fewer side effects than lower ones. but it certainly doesn't seem very likely. I know with Prozac it certainly didn't work that way for me , when this "magic" pill first hit the market it only came in 20 mg capsules, even though the manufacturers's own research demonstrated that 5 mg worked for almost as many people as 20, with fewer side effects. I found the insomnia and anxiety horrible at 20, had an idiot doctor who when I said, "this doesn't work" had me double to 40, of course I couldn't tolerate that at all and dropped it. 16 years later I decided to give Prozac another try, asked my doctor for the now available liquid version, started at 1mg/day and worked up over months. Was able to tolerate it that way, but it never did anything for my depression.

Is there supposed to be a synergistic effect between Wellbutrin and Lamictal? Both had unpleasant side effects and no beneficial effects. Definitely had adequate trials of each, again working up over many months.

Cecilia


 

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poster:Cecilia thread:847169
URL: http://www.dr-bob.org/babble/20080814/msgs/847639.html