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Re: The main drawback is the constipation

Posted by Quintal on July 29, 2008, at 13:25:22

In reply to Re: The main drawback is the constipation, posted by okydoky on July 29, 2008, at 11:36:58

People having constipation with buprenorphine might want to try the Suboxone preparation instead. This formulation was found to reduce/eliminate the constipation side effect. Naloxone blocks the opioid receptors as it passes through the GI tract (after being swallowed in saliva). It isn't absorbed from the oral mucosa or GI tract in significant quantities and doesn't intefere with the therapeutic effect of buprenorphine.





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