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Re: Are the 'Z-drugs' really carcinogenic?

Posted by linkadge on July 5, 2008, at 8:45:13

In reply to Re: Are the 'Z-drugs' really carcinogenic? undopaminergic, posted by Crotale on July 4, 2008, at 11:02:25

> For comparison, antihistamines in general are >neutral, while the antihistamine and serotonin 5->HT2A antagonist cyproheptadine seems to improve >it.

>My experience with antihistamines as sleep aids >is that I build up tolerance to them within a >few days. And when I tried cyproheptadine, it >worsened my mood. Whereas Ambien still works and >I've been taking it for years, practically every >night.

There are no guarentees. I think tollerance builds more completely to antihistamine effects than 5-ht2a antagonist effects. Cyproheptadine can worsen mood. I find it very calming not depressing. The calcium chanel blockade and perhaps nonselective serotonin antagonism might worsen mood. I find it more of a mood stabilizer personally. Melatonergic drugs can sometimes cause depression (possably its anticonvulsant or serotonin modulating effects).

Just because ambien works well doesn't mean it isn't possably carcinogenic.

>I think this guy sounds like he's scaremongering >too.

Possably, but why? Sombody just randomly picks a drug to associate with cancer? Anyhow, I would personnally assume its true until proven false.





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