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Re: Failed on Nardil ....What next???

Posted by undopaminergic on June 30, 2008, at 0:13:35

In reply to Failed on Nardil ....What next???, posted by maoi_wowee on June 27, 2008, at 22:49:59

> -Try Electroshock Therapy?

Too dangerous in my opinion, but even if it would be effective without erasing your memory, you would presumably still need antidepressants in order to prevent relapse into depression.

> -Go back on Parnate?
> -What about Marplan?

You may wish to try Marplan first for comparison, and then decide whether to stay on it or go back on Parnate.

> -Try a new med or med combo that I haven't tried before?

Yes, and since MAOIs apparently work best, your best bet may be a combination of a MAOI with some other drug.

> Here's a list of meds that I've been on over the past 15 years(sure I'm leaving out some):
> Prozac
> Paxil
> Zoloft
> Celexa
> Lexapro

These should not be combined with MAOIs. If serotonergic augmentation is required, tryptophan or 5-HTP may be cautiously tested.

> Wellbutrin
> Ritalin

These are good choices for augmenting MAOIs, and are likely to be safe, but caution is still advised, especially in the beginning of treatment.

> Dexedrine

This drug has more potential for dangerous interactions with MAOIs than the other stimulants, but when it is carefully added at a low dose and titrated in small increments, it can be very safe and highly effective.

> Lithium

This is often a very good choice for augmentation of antidepressant regimens, including MAOIs. Some of the other drugs used as mood-stabilisers are also worth trying - lamotrigine and oxcarbazepine, for example.

> Serzone

This one has been used safely with MAOIs, and may be particularly useful for MAOI-induced insomnia.

> Nortryptaline

This drug, and most other tricyclics, can be safe and sometimes effective as additions to MAOIs. Imipramine and clomipramine, however, should be avoided.

Most opioids are also safe. Buprenorphine is especially suitable.

Some other amino acids that may be useful - beside those mentioned above (tryptophan, etc.) - are phenylalanine and tyrosine. They should be introduced at low doses, as there is some potential for elevation of blood pressure.




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