Posted by undopaminergic on May 26, 2008, at 10:48:18
In reply to Re: This CAN NOT be possible!, posted by mari stella on May 25, 2008, at 19:29:16
> Possibly, the use of this type of stimulant in combination with low doses of sulpiride or amisulpride might be a solution.
> *********Is this something a Dr would be OK with?
I don't think it's a controversial combination in any way, but unfortunately, neither sulpiride nor amisulpride are FDA-approved, so you would probably have to import them.
> > Quite so, but there have been a few reports from people having tolerance problems with amphetamines suggesting that it does work.
> *********Can you show me where? I am desprate for HOPE right now.
See the "Neurotransmitters" board on this site, or search the web for suitable keywords (memantine, amphetamine, tolerance, etc.).
> > Personally, I've found that memantine has some stimulant-like effects of its own, and therefore it's somewhat difficult to say how much of its effects are a result of its reduction of tolerance to stimulants, as opposed to stimulant effects of its own.
> *********WHAT??? Are you saying you dont know if it is working as a tolerance reducer or their just enhancing each other?
Approximately. It's also difficult to rule out the possibility of more complex interactions between the drugs - for example, they may potentiate each other in some ways, and antagonise each other in other ways.
> I AM going to try this and if the mementine helps me get more than 3 days out of adderall then I guess it works. For what I need anyway.
I wish you good luck.
> Therefore, the use of kappa-opioid antagonists like buprenorphine in combination with stimulants is a promising approach to solving the problem of tolerance.
> **********Im on both...obviously no help to me...(whaaaaaa!!!!)
That's quite a coincidence! How often to you take buprenorphine, and at what dose? Do you find tolerance to be a problem with this drug too?