Posted by undopaminergic on May 11, 2008, at 16:22:36
In reply to Very short note on that... » undopaminergic, posted by Racer on May 11, 2008, at 14:14:51
> > Alternatively, addition of Strattera (atomoxetine) to Prozac or Zoloft could be tried, and a further alternative is Cymbalta (duloxetine).
>
> That's a good idea about Strattera, but I'd like to point out that it's contraindicated with Prozac. It's said to be fine with other SSRIs, and I don't know why it's contraindicated with Prozac, but felt I should point out that it was.
>I didn't remember, but the reason is that fluoxetine (Prozac) inhibits the liver enzyme CYP2D6, which metabolises atomoxetine. The combination is not contraindicated, but downward dose adjustment of Strattera is necessary.
poster:undopaminergic
thread:828342
URL: http://www.dr-bob.org/babble/20080510/msgs/828543.html