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Re: modafinil and armodafinil, how do they differ? » SLS

Posted by Larry Hoover on May 11, 2008, at 14:22:22

In reply to Re: modafinil and armodafinil, how do they differ?, posted by SLS on May 11, 2008, at 12:28:07

> > It may be worth emphasising that if you're using modafinil, then you're using armodafinil, because modafinil is a mixture of one part armodafinil, and one part of its mirror image, S-modafinil.
>
> It is interesting, though, that the clinical properties of Lexapro differ from that of Celexa. Lexapro tends to be more stimulating (except at the two-week mark, where it can produce transient fatigue). Some people respond robustly to one and not the other. There was some conjecture that the the r-isomer actually interferes with some of the clinical benefit from the s-isomer.
>
>
> - Scott

It's more than conjecture. R-citalopram is a serotonin reuptake inhibitor inhibitor. It modifies the conformation of the receptor complex by binding at a site other than the active site. The effect is most dramatic in those with one specific serotonin transporter gene allele.

Lar

 

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poster:Larry Hoover thread:828224
URL: http://www.dr-bob.org/babble/20080510/msgs/828503.html