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Wonder Why Wellbutrin was So Bad

Posted by bleauberry on May 8, 2008, at 20:27:20

Wellbutrin in 4 days took me from medium depression to suicidal ideation and almost total incapacitation. Barely able to get through work. Thought I was hiding it pretty well, but at least 5 people commented stuff like, "Smile, it aint that bad", "Don't be so depressed it's a sunny day, "You don't seem like yourself", "Are you ok?" People noticed for sure despite my years of training at hiding it.

Anyway, first two days were the usual wellbutrin stuff...nervousness, heart palpitations, lousy sleep, sweating. I got through that ok. Then third day was total mind numbing calm and deep dark clouds without even a hint of any of the earlier stimulation. Weird also is that sex drive went from normal to absolute zero.

If I ever wanted to feel as bad as anyone could possibly feel, all I need do is take wellbutrin. I've had periods of really really deep bad depression in my life, but it's hard to recall any as bad as what wellbutrin did.

I wonder what mechanism did that?

Doses were only 75mg per day. Scary to think any more might have had me driving my car into a tree to end it all.

It's 24 hours since the final dose so I have hope to return to my baseline within the next day, two or three. Baseline is lousy, but a whole lot better than wellbutrin. I just wonder what mechanism it was that did that. Hard to explain, but it didn't feel like a dopamine thing or a norepinephrine thing. Maybe it was, dunno.


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poster:bleauberry thread:828024
URL: http://www.dr-bob.org/babble/20080430/msgs/828024.html