Posted by undopaminergic on April 23, 2008, at 2:16:42
In reply to Re: Parnate Users-increase in Depression? » Bob, posted by Quintal on April 21, 2008, at 15:16:56
> Because the prescribing guidelines set an upper limit of 30mg here in the UK, in fact I think the PDR in America says the same thing, but most pdocs there seem to prescribe *much* higher doses. I didn't want to continue at 30mg because it made me feel worse in that dose range. I don't know why, but the prescribing advice is too conservative and an awful lot of people that come here are taking more than the recommended maximum dose. The prescribing guidelines recommend lowering the dose to one tablet daily as a maintenance dose, but I've never heard of anyone doing this.
>From the (FDA-approved) prescribing info:
"The usual effective dosage is 30 mg per day, usually given in divided doses. If there are no signs of improvement after a reasonable period (up to 2 weeks), then the dosage may be increased in 10 mg per day increments at intervals of 1 to 3 weeks; the dosage range may be extended to a maximum of 60 mg per day from the usual 30 mg per day."I suspect that anyone needing no more than 30 mg is quite fortunate and exceptional. However, one Parnate expert says most patients respond to 30-50 mg.
poster:undopaminergic
thread:824567
URL: http://www.dr-bob.org/babble/20080420/msgs/824918.html