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Re: Too Much Nardil??

Posted by undopaminergic on April 18, 2008, at 7:18:12

In reply to Too Much Nardil??, posted by maoi_wowee on April 16, 2008, at 21:27:07

> I was on 75mg of Nardil, did great for a few weeks, then depression started to come back so I upped dose to 90mg. Did OK for a few weeks at 90mg, but now my depression has started to come back again.
>
> Any chance that things could get better by decreasing my Nardil dose? Or perhaps by decreasing it down a bunch then upping it again and keeping this cycle going?
>
> Any thoughts/help? I'm lost and desperate
>

They say it's more about time than about dose.

However, dose is certainly not without significance, as it affects the level of MAO inhibiton.

Some sources recommend 1 mg phenelzine per Kg body weight. However, up to at least 135 mg may be necessary. Even then, it may be necessary to add a stimulant - see:
http://www.dr-bob.org/tips/split/MAOIs-in-high-doses-and-wi.html

Personally, I would rather start with a stimulant at high doses, and then add the MAOI, preferably rasagiline, as this would minimise the risk of complications arising from MAO inhibition (dietary and drug interactions).


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URL: http://www.dr-bob.org/babble/20080412/msgs/823980.html