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Re: LOXAPINE WITH ANAFRANIL? » france1000

Posted by yxibow on March 13, 2008, at 4:24:36

In reply to LOXAPINE WITH ANAFRANIL?, posted by france1000 on March 11, 2008, at 5:06:14

>
> > Loxapine is metabolized partially into amoxapine, a tricyclic with antipsychotic properties.
>
> THANK YOUR FOR YOUR ANSWER YXBOY;
> IF LOXAPINE IS METABOLIZED PARTIALLY INTO AMOXAPINE - IS IT USUAL TO COMBINE AMOXAPINE WITH
> ANAFRANIL?
>
>

I should have said, may metabolize fully, partially, it depends on genetics and a whole lot of other things.

Although Amoxapine can be compared to an antipsychotic in some ways, Loxapine is in the official class of one. Amoxapine is an odd and old member of the tricyclic family that possesses some modest D2 blocking capabilities.

Its not usual these days to prescribe Amoxapine, and combining two tricyclics is generally not a practice due to doubling of anticholinergic effects.

Anafranil can have sweating effects for some so it definately has anticholinergic properties.

I would say it would be a very unusual combination.

 

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