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Half-life means duration of drug action?

Posted by Mishal on December 30, 2007, at 23:07:32

If you can help me,

It confuses me when I look at many drugs's half-lifes and the dosage prescribed. For example, Serzone the antidepressant has a very short half-life of maximum 4 hours. Yet it is advised to take twice daily. If the half life of a medicine is only 4 hours, then by taking it twice daily would only make it work for eight hours. Roughly one third of a day (24 hours) Isn't it so?

Or is there any difference between half-life and the duration of drug action?


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poster:Mishal thread:803347
URL: http://www.dr-bob.org/babble/20071225/msgs/803347.html