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Re: A new MAOI being tested (Nardil w/o side effec » tecknohed

Posted by amigan on December 27, 2007, at 16:37:21

In reply to Re: A new MAOI being tested (Nardil w/o side effec, posted by tecknohed on December 26, 2007, at 20:02:49

> > If you are talking about Tyrima, a reversible inhibitor of MAO-A (RIMA); phase I studies has been done this year. Two more to go.
> >
> > /Netch
> >
> > http://www.medicalnewstoday.com/articles/61967.php
>
> If this 'Nardil-like' drug is the RIMA mentioned above then how can it be like Nardil? Nardil inhibits MAO-A & B. That means EXTRA dopamine. Bit like a RIMA plus an MAO-B inhibitor. And where would the GABA effects come from?

How about: Benzodiazepine+moclobemide+selegiline? (GABA+RIMA+MAO-B) Behold the new safe Nardil! :-p


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poster:amigan thread:802518
URL: http://www.dr-bob.org/babble/20071225/msgs/802951.html