Posted by yxibow on December 20, 2007, at 19:59:19
In reply to going from Zyprexa to Seroquel, posted by qbsbrown on December 20, 2007, at 17:24:50
> I've been on a high dose of zyprexa, 30mgs. the med works, but has caused severe weight gain and pre-hypertenson.
>
> Given that I'm a high dose tolerator and fast metabolism, I'm assuming that i will be on a high dose as well
>
> can you crossover from 30mgs zyprex, simply over to say 300mgs seroquel, or start at a lower dose?
>
> Regards,,
>
> Brian
Some doctors might do this but its an iffy proposition, there is no real equivalency like the studies that have been done with benzodiazepines -- and since it isn't being taken for schizophrenia but an affective disorder, who knows what the actual final dose would be for Seroquel. Regardless it isn't an easy transition for any antipsychotic, rebound effects can occur, it depends on the situation.
poster:yxibow
thread:801817
URL: http://www.dr-bob.org/babble/20071213/msgs/801832.html