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Strange reaction on high-dose antidepressants

Posted by Amigan on December 17, 2007, at 7:08:23

I have observed something which i'm not sure how to explain it:

When i take 20-40mg of prozac i feel the restleness that this drug usually gives. Not akathisia, just restleness. The other day, i took 60mg and i was expecting a greater feeling a restleness to kick in. Instead, i began to yawn and didn't felt any stimulation at all.

Likewise, i'm on moclobemide now (aurorix/manerix) (i have stopped taking prozac) and i take 300-600mg daily which gives me a very subtle stimulation. Yesterday, i took 1200mg and i felt rather groggy. Like i was on a hypnotic. I fell asleep for hours.

Is this an idiosyncratic reaction or it is something common? Is there a pharmacological explanation to this?


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poster:Amigan thread:801263
URL: http://www.dr-bob.org/babble/20071213/msgs/801263.html