Posted by Racer on October 29, 2007, at 10:54:39
In reply to Not enough serotonin/Despiramine, posted by Sheilac on October 29, 2007, at 9:16:13
> I don't think that I was getting enough serotnin from either Emsam or Despiramine. Is there another tricylic that I should try that I could get more of a serotonin reaction?
EMSAM inhibits the production of the enzyme which breaks down catecholamine neurotransmitters. It doesn't cause you to "get" more of any neurotransmitter, it only makes those you synthesis stick around longer. That means that you're getting increased serotonin as well as increased dopamine/norepinephrine.
Amitriptyline targets serotonin a bit more than desipramine does. It might be worth a try. It will likely have more side effects, though.
> I like that neuroepinephrine (spelling?)- it helps me lose weight and stay focused.
I think it's worth remembering that all the "this neurotransmitter does this/that neurotransmitter does the that" is pretty speculative. In this case, you may be mistaking histaminergic activity for serotonergic, etc. The more important question is whether one drug works for you or not -- regardless of what biochemical system it targets. Even drugs in the same class can produce very different results -- such as Paxil versus Prozac. Yes, which neurortransmitter is targetted can be a good starting place, but it's not all there is to it.
Are you going to ask your doctor about options for your bladder?