Posted by tecknohed on October 2, 2007, at 6:39:04
In reply to Clonazepam differs from other benzos?, posted by Amigan on September 27, 2007, at 19:53:09
> I see that clonazepam (klonopin) is much more popular than other benzodiazepines. Why is this? Does it have any pharmacological properties that other benzos lack?
> What i know is that, all benzodiazepines have the same mode of action (more or less) and they only differ in 2 aspects: Half-life and potency. Right or wrong?
Seems clonazepam hase some effect on seretonin also:
Clonazepam appears to also have a secondary effect on the neurotransmitter serotonin. It has shown itself to be highly effective as a short-term (3 weeks) adjunct to SSRI treatment in obsessive-compulsive disorder and clinical depression in reducing SSRI side effects with the combination being superior to SSRI treatment alone in a study funded by the manufacturers of clonazepam, Hoffman LaRoche Inc. Similar results have been found with some other anxiety disorders, but the role of the serotonergic effects enhancing the action of the SSRI treatment remains unclear in these cases due to clonazepam's primary anxiolytic mechanism of action.
Probably why its No1 benzo choice for SP.