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Re: Ears ringing from high dose depakote (divalpro

Posted by DXM on April 21, 2007, at 10:30:55

In reply to Ears ringing from high dose depakote (divalproex)?, posted by bipolarspectrum on April 18, 2007, at 10:50:11

> Hi,
> I take 2500 mg of depakote, divalproex acid, for bipolar...
>
> I just got my blood levels done and it seems im right at the top end of the therapeutic levels, actually above it somewhat...
>
> I have ringing in my ears, not horrendous, but constant, could this result from the high dose depakote?
>
> thanx for any replies,
> bps

Depakote can cause tinnitus. I developed ringing in the years two weeks after starting on Depakote at a much lower dose of about 750mg (I am very sensitive to meds so that's a high dose for me). My tinnitus was exacerbated by poor sleep. The first time I discontinued Depakote the ringing in the ears went away gradually in about 3-4 weeks. Unfortunately, I had to go back on Depakote, but recently (3 weeks ago) again dropped it from my drug cocktail. Tinnitus is still present and especially so when I don't get enough good quality sleep. Hope this helps.

DXM


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