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Re: What's up inside my brain?

Posted by lukeds on April 11, 2007, at 21:34:21

In reply to Re: What's up inside my brain?, posted by linkadge on April 11, 2007, at 18:54:23

> 2. Amisulpride is slightly different from other antipsychotics in that it has higher affinity for presynaptic dopamine autoreceptors than it does for post synaptic receptors. So theoretically it could result in increased post-synaptic d2 receptor agonism. This may not be the case however.

What dosage of amisulpride do you recommend me to start to take instead of sulpiride? (The less the better?)

How long I will have to wait until amisulpride starts to work (approximately)?

Maybe that I have been taking sulpiride so many time that I need to up the dosage from 100mg to 200mg or more?

Also I have read that amisulpride affects dopamine d2 and d3, and sulpiride only d2.
How affects dopamine d3 the dysthymia and the IBS?

> I would personally go by what your gut tells you.

Absolutely I am the slave of my gut.

> If paxil alone was working better, then you could try it alone. Perhaps add something else to help with the IBS. Perhaps low dose TCA, or mirtazapine might help.

Paxil without sulpiride or with sulpiride doesn't work for me anymore. I have taken it after March of 2006 two times. The first from July to September of 2006, and although in the beginning it was well, after a month it pooped out.
The second, 8 weeks ago, and again at the beginnig it went well but after a month AGAIN it pooped out, so no more paxil forever.

Which TCA could be good for the IBS?

Only a bit of Mirtazapine sent me to a sleep of 16 hours, cause I take xanax too, and the interaction of benzodiazepines with Mirtazapine causes sleep and severe tiredness.

Lukeds.


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