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Med interactions Phillipa

Posted by gardenergirl on April 6, 2007, at 12:29:35

In reply to Re: Betrayed and put into what type of condition? Larry Hoover, posted by Phillipa on April 5, 2007, at 19:26:35

Hi Phillipa,
According to Epocrates Serzone increases the level of Xanax, which could result in CNS depression or toxicity due to inhibited liver metabolism. They recommend cutting the Xanax dose in half if you take Serzone with it.

With Valium and Serzone (nefazodone), it MAY increase the Valium levels, and if so results in similar effects as above.

With Lunesta it's reommended to start at 1 mg and then increase to 2 mg, since Serzone can also increase levels of this drug and can affect liver metabolism.

Incidentally, they also recommend caution when using Lunesta and a benzo due to the additive effects increasing the risk of CNS depression.

I put Vitamin C, selenium, and Motrin in the mix, as well, and none of these came back with any issues with any of the other meds: Lunesta, Serzone, Valium, or Xanax. So as far as Epocrates is concerned, there are no harmful interactions with those.

Oh, and btw, Motrin makes me sleepy, too. It's a known side effect. If I have to take a prescription level dose, (I'm allergic to sulfa type NSAIDs), I not only get sleepy, I also retain fluids and get puffy. Bleah. But...eventual pain relief from an injury is worth it.

Hope this helps.






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