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Re: Cymbalta or MILNACIPRAN

Posted by tessellated on March 24, 2007, at 16:22:09

In reply to Cymbalta or MILNACIPRAN » Elroy, posted by marianna7777 on March 21, 2007, at 20:53:19

milnacipran has something closer to a one to one or a one to three ratio of NE to 5HT, whereas cybalta is similar to effexor with a much greater ratio of serotonin to norepinephrine reuptake inhibition.

i don't know why milnacipran isn't in the states, it's very popular in japan due to its lack of sexual side effects. its also thought that it has a lessened "discontinuation syndrome".

its fast acting, and quite safe, and has applications for neuropathic pain, why we have to order over seas is due to FDA or patent approval/cost/profit margin.

most people i've heard prefer milnacipran; cymbalta seems to have more side effects.


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