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Do NOT mix alcohol w/ major hypotensives » Sandra62

Posted by yxibow on March 8, 2007, at 1:45:39

In reply to Do NOT mix alcohol with Seroquel!, posted by Sandra62 on March 6, 2007, at 19:03:56

> I just had a very frightening experience. I have recently started 300 mg of Seroquel at night. I went out for some beers and came home and took a dose and I blacked out. At 6:00 a.m. I got up to feed my dogs and could barely walk. I fell down in the kitchen breaking the scoop cups and dog food was everywhere. I hit the side of my eyebrow and it feels like a bruise but didn't turn into one. Anyways, just a warning to those who are taking Seroquel. I will never drink again! I'm so glad to be alive to tell the tale!


The reason you blacked out is not because of an antipsychotic -- it is because of the unique properties of Seroquel. It frequently causes orthostatic hypotension, or low blood pressure. This is part of the H1 antihistamine reaction and is part of the reason for sleepyness and why some people take a very small amount for sleep (because only H1 is activated at that level).


The same can be said for Trazodone, which is probably also the reason priapisms occur because blood can flow in different ways, in males.


I had a similar tale with Trazodone. I had most of a bottle of hard cider and I had thought I had cleared it from my system, but obviously not. I took the Trazodone, had to get up to use the loo, and found myself 2 hours later on the ground of a bathroom floor at an acquaintance's having blacked out. It was the only time I blacked out in my life.


Now were you in life threatening danger, who knows -- depends if you hit a ceramic counter or something. But the same can be said for all things. It's also a very not good idea to down a shot of tequila after taking propranolol.


Point being, don't take alcohol within a few hours or the half life of a an agent that causes or is intended to cause low blood pressure


-- glad you're safe

-- tidings

Jay

 

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