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Interlude Emsamo - Reflections on A Drug Holiday.

Posted by Edwin Ransom on February 21, 2007, at 20:49:57

I am 'enjoying' a drug holiday from Emsam 6 mg/day, in the hopes of regaining the edge in sleep quality it gave me (I'm narcoleptic)

Although I am less organized and more forgetful, I am experiencing a wider range of emotions (both positive and negative) and these emotions are more contextual (i.e. they are appropriate responses to enviromental stimuli, as opposed to just random mood swings)

A hypothesis - those individuals who report 'new' symptoms after being on a drug for awhile, or after quiting (such as PSSD) will be more likely to have an unsuccesful holiday than those who do not. My theory behind this: new symptoms indicate more cascading gene expression (where one gene turns on in response to the drug and then turns others on). A person experiencing a more complex cascade will not revert as quickly (or at all) to their pre-drug brain function. On the other hand, if a person is experiencing mere tolerance - that is more likely to be the result of less complex cascades. These people will approach pre-drug brain function more quickly.

I also wonder whether quitting 'cold turkey' makes it less likely to have a succesful holiday or more likely, or neither.


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