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Re: Antipsychotics+motivation » Klavot

Posted by Quintal on February 17, 2007, at 17:57:04

In reply to Re: Antipsychotics+motivation, posted by Klavot on February 17, 2007, at 17:33:05

Were you referring to Solian (amisulpride) perchance? Amisulpride enhances dopaminergic transmission at doses of 50mg and below by blocking presynaptic autoreceptors (which are a feedback mechanism for controlling dopamine production and release into the synapse). This results in higher dopamine levels in the synapse and hence the pro-motivational effects.

Amisulpride and sulpiride are unique in doing this as far as I'm aware.

Q


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