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Re: Antipsychotics+motivation

Posted by Klavot on February 17, 2007, at 17:33:05

In reply to Re: Antipsychotics+motivation » Klavot, posted by Quintal on February 17, 2007, at 16:48:02

I may well be wrong; I'm certainly no expert on neuroleptics. I was under the impression that low dose APs have a pro-motivational effect, but apparently not. Yes, that makes sense.

Mmm... Just forget I said anything.

Thanks anyway.

Klavot

> >If antipsychotics lower dopaminergic activity then why do they have a pro-motivational effect?
>
> You're the first person I've heard to say antipsychotics have a pro-motivational effect. They're notoriously anti-motivational and that's partly why they're used in prisons and psychiatric hospitals to subdue violent and disruptive individuals, not just because of their antipsychotic effect. I suppose some people who have *severe* depression or paralyzing anxiety might find their ability act on their desires improved after those obstacles are removed or reduced somewhat, but it would be a little misleading to extrapolate that into saying antipsychotics are pro-motivational.
>
> Some newer antipsychotic drugs such as Abilify might help motivation, but Abilify has a different effect at D2 receptors being a partial agonist rather than an antagonist.
>
> Q


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poster:Klavot thread:733596
URL: http://www.dr-bob.org/babble/20070213/msgs/733670.html