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Re: alprazolam, lorazepam and SSRIs

Posted by psychobot5000 on February 2, 2007, at 17:27:20

In reply to Re: (technical) What makes alprazolam seem so pot, posted by bassman on January 31, 2007, at 17:50:27

> 0.75 to 1.25 mg/day. I find that the combination of alprazolam and an SSRI works well, and just an SSRI doesn't. I don't know why.
>

I just yesterday read a study, wherein researchers checked whether lorazepam (ativan) would block the antidepressant effect of paroxetine. I believe they had placebo, paroxetine (paxil), and paroxetine + lorazepam groups of depressed patients.

Contrary to expectations, they found a higher likelihood of remission in the lorazepam + paxil group, than with paxil alone. (Something like 80% to 57% in remission). The data indicate lorazepam (and possibly alprazolam too?) is an effective adjunct to SSRIs. It's a very statistically significant result.


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URL: http://www.dr-bob.org/babble/20070201/msgs/729144.html