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Re: chiral molecules?

Posted by notfred on January 7, 2007, at 12:23:01

In reply to Re: chiral molecules?, posted by naughtypuppy on January 7, 2007, at 10:58:18

> Perhaps the coating/fillers have something to do with the point in the digestive system that the active ingredient is most readily absorbed. Something like Depakote which is absorbed in the small intestine since stomach acids break it down. Or like time released capsules.
>


That is the major difference between brand and generic. The actives remain the same, and often made by the brand manufacure. In any case lorazepam is lorazepam is lorazepam no matter who made it.

coatings/fillers/binders effect how much drug is taken up by the system. You cannot just take the raw active compound and expect to absorb it properly. There is a lot of science in delivering and absorbing the drug into the body. This is where the differences between generic and brand play out, if any.


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URL: http://www.dr-bob.org/babble/20070107/msgs/720174.html