Posted by NYCguy on December 22, 2006, at 18:20:55
In reply to Re: Social Anxiety in the EXTREME!!! Advice Request. » NYCguy, posted by blueberry1 on December 22, 2006, at 17:46:18
> You said you've taken just about everything there is. Ok. Did you get a little bit of help from any of them?
Yes. I got some help from a Cymbalta 60mg/ Klonopin 6mg per day/ Adderall XR 40-60mg per day combo for the better part of a year. In reality, it was only decent if I took the Adderall for four days and then slept the next two days. We thought I had ADHD, but I just couldn't sustain the Adderall for very long otherwise I would crash hard. PStims don't seem to be a very good long-term solution to depression. At least not for me anyway.
If so, maybe choose that one and just take a low dose as kind of a background thing for other stuff. But probably the real trick will be to raise the klonopin dose, or to try xanax, or diazepam. In any case, your dose is pretty low considering the severity of the symptoms.
>Do you think a different Benzo might be less depressing? I'm tapering down off the Klonopin because all it seems to do above my current dose is make me more depressed.
> High dose effexor, paxil, zoloft, clomipramine...sure they can work but for most people the side effect burden would be almost as bad as the condition being treated.
>
> Most people wouldn't consider ordering a med from overseas. But if you did, amisulpride (its name overseas is Solian) at 50mg per day along with your klonopin could be amazing. In the remote chance you are interested...
>I've tried Stablon and Ixel in the past, so that's no big deal. I also tried Geodon and Seroquel in the low dose. I don't know if low dose Solian would be the same type of approach as low dose Seroquel. Might be worth a try..
> Solian was tested against paxil for anxiety and depression. Both were similar in response, except that solian had the added bonus of significantly boosting psychosocial functioning, which paxil didn't. Amisulpride low dose is known for its antidepressant, antianxiety, and pro-motivation pro-interest pro-pleasure qualities. The first week or so it can have some anxiety, insomnia, agitation type side effects. After that it is very tame. The only lingering side effect really is sexual dysfunction requiring viagra for males. I tried it 10 years ago, am expecting an order to arrive soon, and it was an amazing medication for feeling perfectly comfortable in a crowd. It goes well with benzos. It is an antipsychotic at high doses (300mg - 800mg), but an antidepressant at low doses (25mg - 100mg). Since it stimulates dopamine at low doses, it does not make sense to me how it can work for social anxiety, but it just does. It is very clean affecting on 2 specific receptors in very specific parts of the brain.
>
> Low dose zyprexa would probably help a lot. I shy away from mentioning it though, because it is very dirty...hits all kinds of receptors, changes metabolic and hormonal stuff, risk of blood sugar problems or diabetes. But for fast action, it sure can work. I've been on it for 10 years. I used to like it and now I hate it. My friend turned nasty on me. Solian is so much cleaner and more effective.
>Does Solian cause binge eating like many of the other atypicals tend to do? Did you ever get any EPS symptoms from the Zyprexa?
> Just a thought. I only mention it because you say you've tried everything else. And I wouldn't want to mention something that has heavy side effects. Short of that, increase the klonopin dose.
>
> Just opinions. I hope this is helpful.Yes, it is very helpful! Thank you.
poster:NYCguy
thread:715719
URL: http://www.dr-bob.org/babble/20061217/msgs/715756.html