Posted by blueberry on November 21, 2006, at 8:52:04
They exhibited an inhibitory effect on MAO-B. The IC(50) values of the four potent flavonoids, quercitrin, isoquercitrin, rutin, and quercetin on monoamine oxidase were 19.06, 11.64, 3.89, and 10.89 microM and enzyme kinetics analysis revealed apparent inhibition constants (K(i)) of 21.01, 2.72, 1.83, and 7.95 microM, respectively...
I see this a lot in medication studies...IC(50), microM, Ki...can anyone explain how to understand this stuff? What do these letters and numbers mean?
For example, above, quercetin has the highest numbers. Does that mean it is the weakest or the strongest? And in what spectrum range do its numbers fall? I mean, those numbers are relative to what?
Confused.
poster:blueberry
thread:705776
URL: http://www.dr-bob.org/babble/20061117/msgs/705776.html