Posted by Morhoun on November 20, 2006, at 13:25:57
In reply to Re: Question for Parnate users » Morhoun, posted by Quintal on November 19, 2006, at 16:14:17
> I took Parnate earlier this year for social anxiety and mood problems similar to the ones you are describing. I was prescribed 30mg/day but found this made my depression and anxiety worse. I was feeling so bad that soon I began to take more as I noticed that the MAOI veterans posting on this board who had the most success were generally taking much more than 30mg. At doses higher than 40mg I found Parnate had a similar effect on me to cocaine. I began the day by getting a large hit of 30mg as soon as I woke up and continued to pop pills throughout the day 'as needed' to give me a boost whenever I felt my mood or energy dip. At night the stimulant effect of Parnate wore off and the sedative effect of the Klonopin I was taking took over and I would fall into a stupor.
> By the end of the fourth week I was taking somewhere between 80-120mg Parnate a day. I had to come off it as my pdoc stuck rigidly to the 30mg limit stated in the BNF and claimed higher doses could only be harmful. Many people take Parnate but only a few abuse it as I seem to have done, so I hope that does not deter you.
> I had no sexual dysfunction while taking Parnate, in fact my sex drive seemed to increase after taking a dose. Sexual dysfunction is a side effect I find intolerable and get quite a lot with other antidepressants so I would recommend Parnate to you on those grounds.
> Since you have found dopamine agonists effective for your depression may I suggest Amisulpride? Amisulpride is an atypical antipsychotic that is a dopamine agonist at low doses. It is not available in the US however, but Cabergoline - a dopamine agonist drug licensed for Parkinson's Disease may be a reasonable alternative if the pdoc is willing to experiment. Here is a link to a current thread about dopamine agonists that I you think may find useful: http://www.dr-bob.org/babble/20061110/msgs/703230.html
Yah, I was reading that thread yesterday actually. I'm also looking at Abilify. Thanks for the input.