Posted by Quintal on November 18, 2006, at 14:14:21
In reply to Re: Dopamine - Do you care about those Agonists ? » Quintal, posted by erik98225 on November 18, 2006, at 13:23:05
I was thinking about trying a nicotine inhaler a while ago myself for anxiety and depression as tobacco seems to help many people with these problems, but I would prefer to avoid the tar. I was put off by the addiction potential but I found a few other things that may be an acceptable substitute such as the Alzhimer's drug Galantamine. I may still try it now you've brought it to mind. Galantamine is a acetylcholinesterase inhibitor that also acts at nicotinic cholinergic receptor sites. I imagine that is a complicated way of saying it acts like nicotine?
Tobacco smoke also contains harmaline, a mild MAOI which no doubt plays a role in its antidepressant action? I think I would stick with the tobacco rather than risk a relapse into alcohol too.
SSRIs do work for me, up to a point, but I start to hate the fake saccharine sweet happiness after a while, and even that tends to fade and leave me flat and emotionless like a robot. I was 17 when I took my first SSRI - paroxetine - the anorgasmia scared me as I'd read a letter from a guy asking the manufacturer when he would be able to have an orgasm again since he'd stopped the drug six months previously and still could not ejaculate. They totally blanked him and that made me wary so I came off it, and looking back I think that was a wise decision.
I have been wondering if I have a form of Tourettes myself after reading a book called 'Life, interrupted' by James McConnel this summer. I recognised some of my own eccentric traits and mannerisms, and also the intrusive thoughts and desires. I often get an overwhelming urge to do or say something very offensive in public, but thankfully this usually dissolves in to a fit of giggles, which is bad enough in itself though. In a more conservative family I may well have been locked up and put on haloperidol myself by now.