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Re: Dopamine - Do you care about those Agonists ? » Quintal

Posted by erik98225 on November 18, 2006, at 13:23:05

In reply to Re: Dopamine - Do you care about those Agonists ? » erik98225, posted by Quintal on November 18, 2006, at 10:31:35

> Does anyone else find that dopamine agonists generally make them feel light and energetic while antagonists make them feel heavy and tired? I find the mood brightening effect of amisulpride (D2 agonist) more satisfying and substantial than that produced by the SSRIs.

You couldn't have said it better; I fully agree with this. Taking Haldol or Seroquel was miserable -- in the case of Seroquel, I took one pill and about 10 minutes later I wished I was dead and flushed the rest of the Seroquel down the toilet. I REALLY don't tolerate the anticholinergic crap. (I am a smoker; not trying to quit right now because I'm recently quit the much more dangerous Alcohol. I've heard that nicotine is a PROCHOLINERGIC.)

High dose Lyrica (600 mg taken as 300 BID) definitely makes me more energetic, and I suspect it has some sort of dopamine agonist effect.

SSRI's work for me (I've been on paroxetine and citalopram in various times in the past), but they make you gain weight and they ruin your sex life. Not worth it for me; the Lyrica is moch better. I have primary SP with secondary depression and "possible" tourettes.

Erik


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URL: http://www.dr-bob.org/babble/20061117/msgs/704889.html