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Re: neuroleptics+depression..(and apathy)

Posted by linkadge on October 20, 2006, at 18:22:40

In reply to Re: neuroleptics+depression..(and apathy) linkadge, posted by Jay on October 20, 2006, at 15:42:44

Well, perhaps my statement was a bit of an overgeneralization. I suppose some people do find them effective for depression. Some people find that they make their depression worse.

Zyprexa was ok for sleep for me, but it seemed like such a high price to pay the next day, just for a med that got you to sleep.

One other consideration I heard somebody call into question was the following: While it is true that blockade of serotonin 5-ht2a/2c receptors will result in dopamine release in certain areas of the brain, the neuroleptic itself is going to block the some of the actions of that released dopamine, through dopamine receptor antagonism. So what is the net effect on receptor activation? I don't think we know.

Linkadge


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poster:linkadge thread:696107
URL: http://www.dr-bob.org/babble/20061020/msgs/696367.html