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Re: how to prevent wellbutrin poopout? augmentatio

Posted by SLS on October 12, 2006, at 6:01:44

In reply to how to prevent wellbutrin poopout? augmentation?, posted by iforgotmypassword on October 12, 2006, at 2:46:12

> if i were to try wellbutrin again, would lamotrigine or topamax help keep away poopout? due to their impeding effects on glutamate release? anything else maybe? maybe even memantine or amantadine (if amantadine really is a meaningful NMDA antagonist)?

I wasn't aware that Topamax was a GLU release inhibitor. That's interesting. Perhaps you can find me something on that.

(1/2 hour later) I just did some research, and found that Topamax negatively modulates AMPA/kainate glutamate receptors, effectively antagonizing them. I'll have to update my chart.

My doctor is having quite a bit of success with Wellbutrin + Lamictal combination. Others here have described a synergistic energizing effect from the combination.

- Scott




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