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Re: Goldshield Parnate

Posted by willyee on October 11, 2006, at 17:36:40

In reply to Goldshield Parnate shasling, posted by Tomatheus on October 11, 2006, at 9:54:23

> Suzie,
>
> It's interesting to read that you felt manic on the Goldshield Parnate. If you don't mind me asking, how long were you on the Goldshield Parnate? Did your manic symptoms become stronger, weaker, or pretty much stay the same after spending more time at a given dose? Did you try taking just 10 mg/day of the Goldshield Parnate for at least a somewhat extended period of time (at least 2-3 weeks)? If so, what was your response? Finally, how did your response to the Goldshield Parnate differ from your response to the GlaxoSmithKline Parnate?
>
> I'm just curious because I've tried Parnate myself and ended up stopping it prematurely (after about two weeks) because the midday fatigue was just too much for me. I know that a certain amount of early-onset fatigue is generally to be expected when taking MAOIs (when I was able to get my partially homemade enteric version of the Australian Nardil to work, I had to endure about a week and a half of extreme daytime sleepiness after each dose increase before I could start to feel the drug's effects). However, based on the anecdotal reports that I've read from patients who've taken Parnate long-term, it seems that midday fatigue tends to be a long-term problem for those who use the GlaxoSmithKline Parnate these days. This trend seems to be inconsistent with research reports that I've read on the effects of Parnate (which were from studies that were conducted before the Parnate formulation change in the early 1990s), which suggest that Parnate is highly activating. So, even though I can't say for sure that the formulation change somehow made the GlaxoSmithKline Parnate less activating than it used to be, I think that there's some reason to suspect that that may have been the case.
>
> That's why I'm curious about this Goldshield Parnate. It sounds like it may be more activating than the "new" GlaxoSmithKline Parnate. In your experience, did you find this to be the case? I'm wondering if the Goldshield Parnate may be more like the "old" SmithKlineBeecher Parnate.
>
> Anyway, please feel free to answer any of my questions that you'd feel comfortable answering, if you get the chance. I'd appreciate any help that you could provide.
>
> Thanks,
> Tomatheus
>
> > Will, Maybe a dumb question as I have not reviewed all of your posts, but can you back off the Goldshield parnate? Surely thats the source of the mania. It did the same to me and I only took two a day.
> >
> > Anything I can do to help let me know,
> >
> > Suzie
>
>


I have to disagree,when parnate on its first year DID work for me,the glaxco brand,its stimulation and mood elevating effect were a thousand times,no a million times better than what i experiance on this stuff.

Just me of course.Also the re formulation of parnate was much different than nardils,its only a inactive coloring i believe,and there are no cases of it becomming ineffective around that exact point.Nardil users have pretty much pin pointed the change.

Parnate is still encetric coated,unlike the new nardil.This is not to say i dont believe the company could still have made some sort of change,something has to give to the differance.


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poster:willyee thread:693461
URL: http://www.dr-bob.org/babble/20061011/msgs/693913.html