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Amisulpride stopped--bradycardia, sedation

Posted by psychobot5000 on August 31, 2006, at 23:56:44

Hi,

On or around day eight of my trial with amisulpride, which had offered a modest benefit for my mood, I stopped the medication, on an associate's medical advice, because of bradycardia, and combination with another -potentially- heart-dangerous med.

But my final feeling on it, was that it improved my mood, just a little, and perhaps my mental functioning (I suffer from either depressive pseudodementia, or innattentive ADD--it's all in how you interpret the symptoms). But unfortunately, the med sedated me considerably, and I can't say it did anything for my motivation.

It's possible I could've built up enough tolerance to the sedation to get by, especially if the dose were lowered to 25mg, but the slowed heart rate seemed to make attempting that a bad idea.

I'm trying ropinirole now, and hoping for positive effects. Ironically, the main side-effect so far (day 2) is sedation. Oh, well.

If this doesn't work out, I'm considering pindolol--as augmentation for tianeptine. Who knows how that would work out, but if pindolol works through 5-HT 1a antagonism, then I don't believe their mechanisms of action would be in conflict (?).

Well, if the Requip sedation doesn't pass, then I may just see.

P-bot


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poster:psychobot5000 thread:681939
URL: http://www.dr-bob.org/babble/20060825/msgs/681939.html