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Re: RU-486 for depression...

Posted by SLS on July 11, 2006, at 6:33:40

In reply to RU-486 for depression..., posted by med_empowered on July 11, 2006, at 1:54:20

> Since this drug has been around for a while in both the US and internationally, does that mean docs will just use this form off-label? Or is a more expen$ive, "improved" product in development?

I am not aware of any other cortisol receptor antagonists in the pipeline. I imagine there is some interest, though.

Mifepristone is not available by prescription. When used for medical abortion, it is available only directly to physicians who meet certain criteria set forth by the FDA. Patients must sign a patient agreement and agree to return for subsequent visits. When used for depression, a IND must be submitted to the FDA and a petition made to the Feminist Majority Foundation for a supply of the drug under a compassionate use protocol. Of course, the drug is also available in investigative studies.


- Scott

 

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