Posted by Donna Louise on June 7, 2006, at 6:07:15
In reply to Re: Endogenous (Chemistry) vs. Exogenous (Life Eve, posted by pulse on June 6, 2006, at 16:41:45
> no, far as anything i've ever read or experienced, unipolar refers to chemical/ endogenous depression.
> exogenous simply means depression coming from the outside, and is also know as reactive depression.
> 'they' say that both forms can be remitted by taking ADs, but also, for the best outcomes ADs + therapy, usually of the talk variety - one on one.
> way back when i did enjoy kramers book 'listening to prozac.'
> not at all sure that i would nowadays...
Yes, I get all that, I just don't understand how he lumps MAOI's in with other AD's as effecting nerve terminals as mechanism for changing transmiter levels. I understand that an MAOI increased levels of neurotransmitters by inhibiting the enzyme that removes them. Not as the others do by either not allowing reuptake at the originating terminal or preventing or overactivating reception at the recieving terminal. It is not important what he says, I just wondered if anyone knew something about this that would shed some light on why he would say that. I should have just printed that paragraph, but maybe the whole thing has been helpful to others unfamiliar with the concepts. I never read listening to prozac. I was afraid of any book at the time that might tell me not to take it, I was so fragile about it, and did not know what it was about. Do you think it is worth a read? I don't know,.. if he is lumping MAOI's with other AD's in terms of how they work....