Posted by ttee on June 2, 2006, at 0:39:23
In reply to Has anybody failed an SSRI,and did well w another?, posted by nickguy on June 1, 2006, at 21:25:02
I failed a couple SSRI's and I am about to switch from the current problem with Lexapro to Zoloft. So I am in your same shoes and curious to what others say to your post.
It is my understanding that in the recent STAR*D large clinical study, they found the switching to another SSRI has about the same chance of producing a response as augmenting the not working SSRI with wellbutrin or buspar, and the about the same as switching to a totally different class of antidepressant.
The biggest advantage to switching between SSRI's is the ease of doing it. Generally, you don't have to tapper the dose of the first med and you can just stop the old SSRI one day and the next start the new SSRI. That is a lot easier than fooling around with med combos or washing out of a med before trying something like Emsam. Please keep us posted on what you decide and how it goes.
> I've tried paxil and lexapro with no results. Not even side effects. My doctor wants to try zoloft before going to other options. Is this worth a shot in anybody's opinion. He says that a lot of people out there say if you've tried one SSRI, you've tried them all, but that that's not true.
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> Has anybody failed to respond to one or more SSRI's, and done well on another>?
poster:ttee
thread:651694
URL: http://www.dr-bob.org/babble/20060530/msgs/651758.html