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Re: Requip for Social Phobia/Depression?

Posted by SLS on March 25, 2006, at 14:15:33

In reply to Re: Requip for Social Phobia/Depression?, posted by kingcolon on March 25, 2006, at 13:39:34

> Regarding Lamictal, it is functionally an NMDA antagonist, by its glutamate antagonism. I believe there is some data on the glutamate system modulating the dopamine system, and I recollect that antiglutaminergic agents potentiated dopamine. I'll look into it further. In any event, if that were the case a combo of Lamictal and a dopamine agonist like Requip might be more effective than either alone.


I think Lamictal might be a glutamate release inhibitor as well as a sodium channel blocker.


- Scott

 

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